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Thalidomide-O-PEG2-propargyl
62 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– Thalidomide-O-PEG2-propargyl (E3 Ligase Ligand-Linker Conjugates 32) is a chemical compound that has been synthesized as a conjugate of an E3 ligase ligand and a linker. It incorporates the cereblon ligand based on Thalidomide, along with a 2-unit PEG linker. This compound is specifically designed for use in PROTAC technology, which utilizes ligand-induced protein degradation [1].
Web ID
– T18826
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C20H20N2O7
References
– Wurz RP, et al. A “Click Chemistry Platform” for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation. J Med Chem. 2018 Jan 25;61(2):453-461.
CAS Number
– 2098487-52-4
Molecular Weight
– C20H20N2O7
SMILES
– O=C1NC(=O)C(N2C(=O)C=3C=CC=C(OCCOCCOCC#C)C3C2=O)CC1
Target
– Others
Pathway
– Others
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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