BAY-707
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BAY-707

SKU T14509-5 mg Category Brand:

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Product Description

– BAY-707, a highly potent and selective substrate-competitive inhibitor of MTH1 (NUDT1) with an IC50 of 2.3 nM, is well-tolerated in mice and exhibits a favorable pharmacokinetic (PK) profile compared to other MTH1 compounds. However, it demonstrates a clear lack of anticancer efficacy both in vitro and in vivo[1].

Web ID

– T14509

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C15H20N4O2

References

– Ellermann M, et al. Novel Class of Potent and Cellularly Active Inhibitors Devalidates MTH1 as Broad-Spectrum Cancer Target.ACS Chem Biol. 2017 Aug 18;12(8):1986-1992.

CAS Number

– 2109805-96-9

Molecular Weight

– C15H20N4O2

SMILES

– C(NCC)(=O)C1=CC2=C(C=CN=C2N1)N3[C@@H](C)COCC3

Target

– Others

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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