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SIM-688
Price range: 243 CAD through 3,136 CAD
Products Details
Product Description
– SIM-688 is a selective and orally active estrogen receptor inhibitor of NF-κB transcriptional activity (IC50 = 122 nM in HAECT-1 cells).
Web ID
– T17252
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C34H31F3N2O2
References
– Caggiano TJ, et al. Estrogen receptor dependent inhibitors of NF-kappaB transcriptional activation-1 synthesis and biological evaluation of substituted 2-cyanopropanoic acid derivatives: pathway selective inhibitors of NF-kappaB, a potential treatment for rheumatoid arthritis. J Med Chem. 2007 Nov 1;50(22):5245-8.
CAS Number
– 796854-35-8
Molecular Weight
– C34H31F3N2O2
Compound Purity
– 0.9912
SMILES
– COc1ccccc1[C@H](c1cccc2ccccc12)[C@@](C)(C#N)C(=O)N1CCC(CC1)c1cccc(c1)C(F)(F)F
Target
– Endogenous Metabolite
Pathway
– Endocrinology/Hormones|||NF-κB
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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