Tazemetostat hydrobromide
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Tazemetostat hydrobromide

SKU T17002-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 58 CAD through 635 CAD

Products Details

Product Description

– Tazemetostat hydrobromide (E-7438 hydrobromide) is a potent and selective EZH2 inhibitor. Tazemetostat hydrobromide inhibits the activity of human polycomb repressive complex 2 (PRC2)-containing wild-type EZH2 (Ki: 2.5 nM). Tazemetostat hydrobromide also inhibits EZH1 (IC50: 392 nM).

Web ID

– T17002

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C34H45BrN4O4

References

– Knutson SK, et al. Durable tumor regression in genetically altered malignant rhabdoid tumors by inhibition of methyltransferaseEZH2. Proc Natl Acad Sci U S A. 2013 May 7;110(19):7922-7.

CAS Number

– 1467052-75-0

Molecular Weight

– C34H45BrN4O4

Compound Purity

– 0.998

SMILES

– O=C(C1=CC(C2=CC=C(CN3CCOCC3)C=C2)=CC(N(CC)C4CCOCC4)=C1C)NCC5=C(C)C=C(C)NC5=O.[H]Br

Target

– CDK|||Carbonic Anhydrase

Pathway

– Chromatin/Epigenetic

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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