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Sulfo-ara-F-NMN
Price range: 3,968 CAD through 10,064 CAD
Products Details
Product Description
– Sulfo-ara-F-NMN is an analogue of nicotinamide mononucleotide (NMN) with cellular permeability. Sulfo-ara-F-NMN was selective to activate SARM1 and inhibited CD38 with an IC50 of about 10 μM. Activation by Sulfo-ara-F-NMN to Z-48 or NMN, which has a higher cyclase activity, causes conformational changes in SARM1, resulting in cADPR production, NAD depletion, and non-apoptotic cell death.
Web ID
– T13907
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C11H14FN2O6PS
References
– Zhao ZY, et al. A Cell-Permeant Mimetic of NMN Activates SARM1 to Produce Cyclic ADP-Ribose and Induce Non-apoptotic Cell Death. iScience. 2019 May 31;15:452-466.
CAS Number
– 1374663-29-2
Molecular Weight
– C11H14FN2O6PS
SMILES
– F[C@@H]1[C@@H](O[C@H](COP(=O)([O-])S)[C@H]1O)[N+]=2C=C(C(N)=O)C=CC2
Target
– Others
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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