PF-06446846 hydrochloride
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PF-06446846 hydrochloride

SKU T16491-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 146 CAD through 3,728 CAD

Products Details

Product Description

– PF-06446846 hydrochloride, an orally active and highly selective inhibitor, targets Proprotein Convertase Subtilisin/Kexin type 9 (PCSK9) translation by inducing ribosomal stalling at approximately codon 34, effectively suppressing PCSK9 expression.

Web ID

– T16491

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H20CIN7O.XHCl

References

– Lintner NG, et al. Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain. PLoS Biol. 2017 Mar 21;15(3):e2001882.

CAS Number

– 1632250-50-0

Compound Purity

– 0.9811

SMILES

– Cl.Clc1cccnc1N([C@@H]1CCCNC1)C(=O)c1ccc(cc1)-n1nnc2cccnc12

Target

– GPCR|||Influenza Virus|||Endogenous Metabolite

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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