JNJ-46281222
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JNJ-46281222

SKU T15618-25 mg Category Brand:

Price range: 2,288 CAD through 5,104 CAD

Products Details

Product Description

– JNJ-46281222 is a metabotropic glutamate (mGlu) 2-selective, highly potent positive allosteric modulator (PAM) with nanomolar affinity (Kd = 1.7 nM) and high modulatory potency (pEC50 = 7.71).

Web ID

– T15618

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H25F3N4

References

– Doornbos ML,et al. Molecular mechanism of positive allosteric modulation of the metabotropic glutamate receptor 2 by JNJ-46281222.Br J Pharmacol. 2016 Feb;173(3):588-600.

CAS Number

– 1254980-38-5

Molecular Weight

– C23H25F3N4

SMILES

– FC(F)(F)c1c(CN2CCC(CC2)c2ccccc2)ccn2c(CC3CC3)nnc12

Target

– Phosphatase

Pathway

– Neuroscience

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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