TD-0212 TFA
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TD-0212 TFA

SKU T13125L-25 mg Category Brand:

Price range: 4,352 CAD through 7,840 CAD

Products Details

Product Description

– TD-0212 TFA is an orally active dual pharmacology compound, functioning as an antagonist of the angiotensin II type 1 receptor (AT1) with a pKi of 8.9, and as an inhibitor of neprilysin (NEP) with a pIC50 of 9.2.

Web ID

– T13125L

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C30H35F4N3O6S

References

– McKinnell RM, et al. Discovery of TD-0212, an Orally Active Dual Pharmacology AT1 Antagonist and Neprilysin Inhibitor (ARNI). ACS Med Chem Lett. 2018 Dec 3;10(1):86-91.

CAS Number

– 1073549-11-7

Molecular Weight

– C30H35F4N3O6S

SMILES

– OC(=O)C(F)(F)F.CCOc1nc(CC)c(CNC(=O)[C@@H](S)CC(C)C)n1Cc1ccc(cc1F)-c1ccccc1C(O)=O

Target

– GluR

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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