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TAS-114
478 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– TAS-114 is an orally active dual inhibitor of dUTPase and dihydropyrimidine dehydrogenase (DPD). TAS-114 targets the intercellular metabolism of 5-FU to enhance antitumor activity and modulates catabolic pathways to improve the systemic availability of 5-FU.
Web ID
– T13089
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C21H29N3O6S
References
– Yano W, et al. TAS-114, a First-in-Class Dual dUTPase/DPD Inhibitor, Demonstrates Potential to Improve Therapeutic Efficacy of Fluoropyrimidine-Based Chemotherapy. Mol Cancer Ther. 2018 Aug;17(8):1683-1693.
CAS Number
– 1198221-21-4
Molecular Weight
– C21H29N3O6S
Compound Purity
– 0.9976
SMILES
– C[C@@H](NS(=O)(=O)CCCOCn1ccc(=O)[nH]c1=O)c1cccc(OC2CCCC2)c1
Target
– Others
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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