Talmapimod
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Talmapimod

SKU T12871-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 77 CAD through 1,349 CAD

Products Details

Product Description

– Talmapimod (SCIO-469) is a selective, orally active, ATP-competitive p38α inhibitor with IC50 values of 9 nM for p38α and 90 nM for p38β. Talmapimod exhibits at least 2000-fold selectivity over a panel of 20 kinases, including other MAPKs.

Web ID

– T12871

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C27H30ClFN4O3

References

– Hideshima T et al. p38 MAPK inhibition enhances PS-341 (bortezomib)-induced cytotoxicity against multiple myeloma cells. Oncogene. 2004 Nov 18, 23(54), 8766-76.

CAS Number

– 309913-83-5

Molecular Weight

– C27H30ClFN4O3

Compound Purity

– 0.999

SMILES

– C[C@H]1CN([C@H](C)CN1Cc1ccc(F)cc1)C(=O)c1cc2c(cn(C)c2cc1Cl)C(=O)C(=O)N(C)C

Target

– Adenosine Receptor

Pathway

– MAPK

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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