(R)-CR8 trihydrochloride

SKU T12617-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 56 CAD through 782 CAD

Products Details

Product Description

– (R)-CR8 trihydrochloride (CR8, (R)-Isomer trihydrochloride) is a CDK1/2/5/7/9 inhibitor that acts as a molecular glue degrader with neuroprotective activity and induces apoptosis.

Web ID

– T12617

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C24H32Cl3N7O

References

– Bettayeb K, et al. CR8, a potent and selective, roscovitine-derived inhibitor of cyclin-dependent kinases. Oncogene. 2008 Oct 2;27(44):5797-807.

CAS Number

– 1786438-30-9

Molecular Weight

– C24H32Cl3N7O

Compound Purity

– 0.9933

SMILES

– Cl.Cl.Cl.CC[C@H](CO)Nc1nc(NCc2ccc(cc2)-c2ccccn2)c2ncn(C(C)C)c2n1

Target

– Others

Pathway

– Cell Cycle/Checkpoint|||Apoptosis

Product type

– PROTAC

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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