Dxd
Add to CompareAdded to Compare

Download Files:

Dxd

SKU T11249L-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 62 CAD through 373 CAD

Products Details

Product Description

– Dxd (OQM5SD32BQ) is a potent inhibitor of DNA topoisomerase I with an IC50 of 0.31 μM. It is used as a conjugated drug of HER2-targeting ADC.

Web ID

– T11249L

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C26H24FN3O6

References

– Ogitani Y, et al. DS-8201a, A Novel HER2-Targeting ADC with a Novel DNA Topoisomerase I Inhibitor, Demonstrates a Promising Antitumor Efficacy with Differentiation from T-DM1. Clin Cancer Res. 2016 Oct 15;22(20):5097-5108.

CAS Number

– 1599440-33-1

Molecular Weight

– C26H24FN3O6

Compound Purity

– 0.9985

SMILES

– CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc(F)c(C)c5CC[C@H](NC(=O)CO)c(c3Cn1c2=O)c45

Target

– FXR|||Autophagy

Pathway

– DNA Damage/DNA Repair|||Antibody-drug Conjugate/ADC Related

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

Related Products

Select options
MD-224
MD-224 Price range: 102 CAD through 2,160 CAD
1 mg1 mL * 10 mM (in DMSO)5 mg

1000 in stock

Select options
FKBP12 PROTAC dTAG-13
FKBP12 PROTAC dTAG-13 Price range: 118 CAD through 261 CAD
1 mg25 mg5 mg

1000 in stock

Select options
Eragidomide
Eragidomide Price range: 54 CAD through 1,160 CAD
1 mg1 mL * 10 mM (in DMSO)5 mg

1000 in stock

Select options
Androgen receptor antagonist 1
Androgen receptor antagonist 1 Price range: 2,432 CAD through 4,000 CAD
100 mg25 mg50 mg

1000 in stock

Add to cart
N-Boc-4-hydroxy-L-proline methyl ester
N-Boc-4-hydroxy-L-proline methyl ester 46 CAD

1000 in stock

My Cart
Wishlist
Recently Viewed
Categories

Request Data Sheet / Safty Data Sheet

Please enable JavaScript in your browser to complete this form.
=

Price Request

Please enable JavaScript in your browser to complete this form.
=

Compare Products (0 Products)
document.addEventListener('elementor/popup/show', function() { if (typeof turnstile !== 'undefined') { document.querySelectorAll('.cf-turnstile').forEach(function(el) { if (!el.dataset.rendered) { turnstile.render(el); el.dataset.rendered = true; } }); } });