Giredestrant tartrate

SKU T11236-1 mg Category Brand:

Price range: 187 CAD through 1,808 CAD

Products Details

Product Description

– Giredestrant tartrate (Estrogen receptor antagonist 1) is a novel, orally active, selective and effective non-steroidal estrogen receptor antagonist. Giredestrant tartrate strongly binds to ER, resulting in the failure of ER to activate the transcription of targeted genes and promoting the degradation of ER protein. Giredestrant tartrate can be used to treat tumor diseases.

Web ID

– T11236

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C31H37F5N4O7

References

– Liang J, Zbieg JR, Blake RA, et al. GDC-9545 (Giredestrant): A Potent and Orally Bioavailable Selective Estrogen Receptor Antagonist and Degrader with an Exceptional Preclinical Profile for ER+ Breast Cancer. J Med Chem. 2021;64(16):11841-11856.

CAS Number

– 2407529-33-1

Molecular Weight

– C31H37F5N4O7

Compound Purity

– 0.9801

SMILES

– [C@@H]([C@H](C(O)=O)O)(C(O)=O)O.C(C(CO)(F)F)N1[C@@H](C2=C(C=3C(N2)=CC=CC3)C[C@H]1C)C4=C(F)C=C(NC5CN(CCCF)C5)C=C4F

Target

– Others

Pathway

– Endocrinology/Hormones

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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