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EGFR-IN-9
Price range: 77 CAD through 846 CAD
Products Details
Product Description
– EGFR-IN-9 is a potent EGFR kinase inhibitor with IC50s of 7 nM, 28 nM for the wild type EGFR kinase and double mutant EGFR kinase (L858R/T790M). EGFR-IN-9 has antitumor activity.
Web ID
– T11163
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C29H24N4O3
References
– Coumar MS, et al. Fast-forwarding hit to lead: aurora and epidermal growth factor receptor kinase inhibitor leadidentification. J Med Chem. 2010 Jul 8;53(13):4980-8.
CAS Number
– 1226549-39-8
Molecular Weight
– C29H24N4O3
Compound Purity
– 0.998
SMILES
– OC[C@@H](Nc1ncnc2oc(c(-c3cccc(NC(=O)C=C)c3)c12)-c1ccccc1)c1ccccc1
Target
– Apoptosis|||Nucleoside Antimetabolite/Analog|||Autophagy
Pathway
– JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Angiogenesis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
