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BI-749327
Price range: 216 CAD through 3,712 CAD
Products Details
Product Description
– BI-749327 is a high selectivity and orally bioavailable antagonist of TRPC6 (IC50s: 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6).
Web ID
– T10537
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C23H21F3N4O2
References
– Lin B L, et al. In vivo selective inhibition of TRPC6 by antagonist BI 749327 ameliorates fibrosis and dysfunction in cardiac and renal disease. Proc Natl Acad Sci U S A. 2019 May 14;116(20):10156-10161.
CAS Number
– 2361241-23-6
Molecular Weight
– C23H21F3N4O2
Compound Purity
– 0.9968
SMILES
– Nc1ccc(nn1)C1CCN(CC1)C(=O)c1ccc(Oc2ccc(cc2)C(F)(F)F)cc1
Target
– Others
Pathway
– Membrane transporter/Ion channel
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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