AV-412
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AV-412

SKU T10419-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 59 CAD through 1,034 CAD

Products Details

Product Description

– AV-412 (MP412) is an EGFR inhibitor for EGFR, EGFR T790M, EGFR L858R, EGFR L858R/T790M, and ErbB2, with IC50 values of 0.75, 0.79, 0.5, 2.3, and 19 nM, respectively.

Web ID

– T10419

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C41H44ClFN6O7S2

References

– Suzuki T, et al. Pharmacological characterization of MP-412 (AV-412), a dual epidermal growth factor receptorand ErbB2 tyrosine kinase inhibitor. Cancer Sci. 2007 Dec;98(12):1977-84.

CAS Number

– 451493-31-5

Molecular Weight

– C41H44ClFN6O7S2

Compound Purity

– 0.9992

SMILES

– Cc1ccc(cc1)S(O)(=O)=O.Cc1ccc(cc1)S(O)(=O)=O.CN1CCN(CC1)C(C)(C)C#Cc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C=C

Target

– Others

Pathway

– Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Angiogenesis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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