AB-680

SKU T10216-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 184 CAD through 2,032 CAD

Products Details

Product Description

– AB-680, a highly potent, reversible, and selective inhibitor of CD73 (an ectonucleotidase, Ki: 4.9 pM for hCD73) with anti-tumor activity, displays >10,000-fold selectivity over related ectonucleotidases CD39.

Web ID

– T10216

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H24ClFN4O9P2

References

– Lawson KV, et al. Discovery and Characterization of AB680, a Potent and Selective Small-Molecule CD73 Inhibitor for Cancer Immunotherapy.

CAS Number

– 2105904-82-1

Molecular Weight

– C20H24ClFN4O9P2

Compound Purity

– 0.9798

SMILES

– N([C@@H](C)C1=C(F)C=CC=C1)C2=C3C(N(N=C3)[C@@H]4O[C@H](COP(CP(=O)(O)O)(=O)O)[C@@H](O)[C@H]4O)=NC(Cl)=C2

Target

– Others

Pathway

– Immunology/Inflammation

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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