Cepharanthine
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Cepharanthine

SKU T0131-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 53 CAD through 312 CAD

Products Details

Product Description

– Cepharanthine (NSC-623442) is a natural alkaloid that inhibits TNF-α-mediated NFκB stimulation, plasma membrane lipid peroxidation, and platelet aggregation, as well as cytokine production. Cepharanthine exhibits anti-inflammatory, antioxidant, and antitumor activities.

Web ID

– T0131

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C37H38N2O6

Citations

– 1. Xiao Y, Cai G P, Feng X, et al.Splicing factor YBX1 regulates bone marrow stromal cell fate during aging.The EMBO Journal.2023: e111762. 2. Chen G, Li J, Liu H, et al.Cepharanthine Ameliorates Pulmonary Fibrosis by Inhibiting the NF-κB/NLRP3 Pathway, Fibroblast-to-Myofibroblast Transition and Inflammation.Molecules.2023, 28(2): 753. 3. Li P, Zhang R, Hu P, et al.Cepharanthine relieves nonalcoholic steatohepatitis through inhibiting STAT1/CXCL10 axis-mediated lipogenesis and inflammatory responses.Journal of Ethnopharmacology.2025: 119358.

References

– Chen Z, et al. Acta Pharmacol Sin, 2012, 33(1), 101-108.

CAS Number

– 481-49-2

Molecular Weight

– C37H38N2O6

Compound Purity

– 0.9981

SMILES

– COc1ccc2C[C@H]3N(C)CCc4cc(OC)c(Oc5c6OCOc6cc6CCN(C)[C@@H](Cc7ccc(Oc1c2)cc7)c56)cc34

Target

– Others

Pathway

– Autophagy|||Apoptosis|||Proteases/Proteasome|||Microbiology/Virology

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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