Epirubicin hydrochloride

SKU T0125-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 53 CAD through 1,323 CAD

Products Details

Product Description

– Epirubicin hydrochloride (Pharmorubicin) is an adriamycin derivative, a topoisomerase (Topo) inhibitor, and a Forkhead box protein p3 (Foxp3) inhibitor. Epirubicin hydrochloride has antitumor activity.

Web ID

– T0125

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C27H30ClNO11

Citations

– 1. Huang Y, Wang H, Hao Y, et al. Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity. Nature Cell Biology. 2020: 1-12.(22-6 , 716–727) 2. Qian S, Han Y, Zhang Y, et al.Discovery of AHCY as an Off-Target of Doxorubicin by Integrative Analysis of Photoaffinity Labeling Chemoproteomics and Untargeted Metabolomics.Analytical Chemistry.2022 3. Zhang S, Kim E J, Huang J, et al.NEAT1 repression by MED12 creates chemosensitivity in p53 wild‐type breast cancer cells.The FEBS Journal.2024

References

– Cersosimo RJ, et al. J Clin Oncol, 1986, 4(3), 425-439.

CAS Number

– 56390-09-1

Molecular Weight

– C27H30ClNO11

Compound Purity

– 0.9979

SMILES

– Cl.COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO

Target

– Autophagy|||Antibacterial|||Antibiotic

Pathway

– Apoptosis|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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