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Products Details
Product Description
– Zoptarelin doxorubicin, also known as AEZS-108, is an LHRH agonist. Zoptarelin doxorubicin is a peptide agonist of the gonadotropin releasing hormone-1 receptor (GnRH-1R) that is conjugated to the anthracycline antibiotic doxorubicin with potential antineoplastic activity. Zoptarelin doxorubicin binds to GnRH-1Rs, which may be highly expressed on endometrial and ovarian tumor cell membrane surfaces, and is internalized. Once inside the cell, the doxorubicin moiety of this agent intercalates into DNA and inhibits the topoisomerase II activity, which may result in the inhibition of tumor cell DNA replication and tumor cell proliferation
Web ID
– T70775
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C91H117N19O26
CAS Number
– 139570-93-7
Molecular Weight
– C91H117N19O26
SMILES
– O([C@@H]1C2=C(C(O)=C3C(=C2O)C(=O)C=4C(C3=O)=CC=CC4OC)C[C@](C(COC(CCCC(NCCCC[C@@H](NC([C@H](CC5=CC=C(O)C=C5)NC([C@@H](NC([C@H](CC=6C=7C(NC6)=CC=CC7)NC([C@H](CC8=CN=CN8)NC(=O)[C@H]9NC(=O)CC9)=O)=O)CO)=O)=O)C(N[C@H](C(N[C@H](C(=O)N%10[C@H](C(NCC(N)=O)=O)CCC%10)CCCNC(=N)N)=O)CC(C)C)=O)=O)=O)=O)(O)C1)[C@H]%11C[C@H](N)[C@H](O)[C@H](C)O%11
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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