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ZL-Pin01
Products Details
Product Description
– ZL-Pin01 is a high potent covalent Pin1 (Peptidyl-Prolyl Isomerase NIMA-Interacting-1) inhibitor. ZL-Pin01 shows potent disruption of the Pin1-substrate interaction with an IC50 of 1.33 μM[1].
Web ID
– HY-143902
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C14H17ClN2O3S
References
– [1]Liu L, et al. Computational and Structure-Based Development of High Potent Cell-Active Covalent Inhibitor Targeting the Peptidyl-Prolyl Isomerase NIMA-Interacting-1 (Pin1). J Med Chem. 2022;65(3):2174-2190.
CAS Number
– 1047464-92-5
Molecular Weight
– 328.81
SMILES
– O=C1CSC2(CCN(C(CCl)=O)CC2)N1CC3=CC=CO3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Others
Pathway
– Others
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.