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Products Details
Product Description
– ZL-Pin01 is a high potent covalent Pin1 (Peptidyl-Prolyl Isomerase NIMA-Interacting-1) inhibitor. ZL-Pin01 shows potent disruption of the Pin1-substrate interaction with an IC50 of 1.33 μM[1].
Web ID
– HY-143902
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C14H17ClN2O3S
References
– [1]Liu L, et al. Computational and Structure-Based Development of High Potent Cell-Active Covalent Inhibitor Targeting the Peptidyl-Prolyl Isomerase NIMA-Interacting-1 (Pin1). J Med Chem. 2022;65(3):2174-2190.
CAS Number
– 1047464-92-5
Molecular Weight
– 328.81
SMILES
– O=C1CSC2(CCN(C(CCl)=O)CC2)N1CC3=CC=CO3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Others
Pathway
– Others
Product type
– Reference compound
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