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Products Details
Product Description
– Z-Gly-Pro-Phe-Leu-CHO (Z-GPFL-CHO) is a tetrapeptide aldehyde that acts as a selective and potent proteasome inhibitor, with inhibition constants (Ki) of 1.5 µM for branched-chain amino acid-preferred, 2.3 µM for small neutral amino acid-preferred, and 40.5 µM for chymotrypsin-like activities, and an inhibitory concentration (IC50) of 3.1 µM for peptidyl-glutamyl peptide hydrolyzing activity [1].
Web ID
– T80735
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C30H38N4O6
CAS Number
– 159659-05-9
Molecular Weight
– C30H38N4O6
SMILES
– C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C=O)=O)(=O)[C@H]2N(C(CNC(OCC3=CC=CC=C3)=O)=O)CCC2
Pathway
– Proteases/Proteasome|||Ubiquitination
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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