Z-AEVD-FMK

SKU T36331-1 mg Category Brand:

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Products Details

Product Description

– Z-AEVD-FMK (Z-Ala-Glu-Val-Asp-Fluoromethyl Ketone) is a degradable ADC linker and caspase-10 inhibitor, reducing TNF-α/butyrate-induced apoptosis, and inhibiting Gal-9-induced apoptosis.

Web ID

– T36331

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C28H39FN4O10

References

– Park, S.J., Wu, C.H., Gordon, J.D., et al. Taxol induces caspase-10-dependent apoptosis. The Journal of Biological Chemisty 279(49), 51057-51067 (2004).

CAS Number

– 1135688-47-9

Molecular Weight

– C28H39FN4O10

SMILES

– [C@H](C(N[C@H](C(N[C@@H](CC(OC)=O)C(CF)=O)=O)C(C)C)=O)(NC([C@@H](NC(OCC1=CC=CC=C1)=O)C)=O)CCC(OC)=O

Target

– Others

Pathway

– Antibody-drug Conjugate/ADC Related

Product type

– Peptide

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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