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Yohimbine
$50
Only 1000 item(s) left in stock.
Web ID
– HY-12715
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C21H26N2O3
Citations
– Biomed Pharmacother. 2022 Apr 26;150:113006.|Eur J Neurosci. 2021 Nov 4.|J Neuroinflammation. 2022 May 27;19(1):123.|J Neurophysiol. 2023 Apr 12.|Eur J Pharmacol. 2023 Nov 6:176174.|Exp Neurobiol. 2020 Oct 31;29(5):356-375.|Mol Biol Rep. 2020 May;47(5):3629-3639.|Mol Med Rep. 2020 Jul;22(1):175-184.|Neurosci Bull. 2022 Apr;38(4):386-402.
References
– [1]Saeed SA, et al. Signaling mechanisms mediated by G-protein coupled receptors in human platelets. Acta Pharmacol Sin. 2004 Jul;25(7):887-892.|[2]Blanchard RJ, et al. Yohimbine potentiates active defensive responses to threatening stimuli in Swiss-Webster mice. Pharmacol Biochem Behav. 1993 Mar;44(3):673-681.|[3]Fuller BB, et al. Downregulation of tyrosinase activity in human melanocyte cell cultures by yohimbine. J Invest Dermatol. 2000 Feb;114(2):268-276.
CAS Number
– 146-48-5
Molecular Weight
– 354.44
Compound Purity
– 99.91
SMILES
– [H][C@]12C(NC3=C4C=CC=C3)=C4CCN1C[C@@]5(CC[C@H](O)[C@H](C(OC)=O)[C@]5(C2)[H])[H]
Clinical Information
– Launched
Research Area
– Neurological Disease; Endocrinology
Solubility
– DMSO : 5 mg/mL (ultrasonic)|H2O : 1 mg/mL (ultrasonic;warming;heat to 80°C)
Target
– Adrenergic Receptor
Isoform
– α adrenergic receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Natural Products
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
