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YAP-TEAD-IN-1 TFA
Price range: 240 CAD through 914 CAD
Products Details
Product Description
– YAP-TEAD-IN-1 TFA, a competitive inhibitor of the YAP–TEAD interaction (IC50: 25 nM), exhibits higher binding affinity to TEAD1 (Kd: 15 nM) compared to YAP (50-171) (Kd: 40 nM).
Web ID
– TP2160L
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C93H144ClN23O21S2.xC2HF3O2
Citations
– 1. Effects of YAP Inhibitors and Activators on the Growth of Leukemia Cells[J]. Anticancer Research, 2025, 45(3): 977-987.
References
– Zhang Z, et al. Structure-Based Design and Synthesis of Potent Cyclic Peptides Inhibiting the YAP-TEAD Protein-Protein Interaction.ACS Med Chem Lett. 2014 Jul 14;5(9):993-8.
CAS Number
– 1659305-79-9
SMILES
– C(C(O)=O)(F)(F)F.C(=O)([C@H]1N(C([C@@H](NC(=O)[C@H]2NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@]4(N(C(=O)[C@H](CCCC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC([C@@H](NC(=O)[C@H]5N(C([C@@H](NC(C)=O)C(C)C)=O)CCC5)CC6=CC(Cl)=CC=C6)=O)CCSSC2)CCC4)[H])CCCCN)=O)CCC1)N7[C@H](C(N[C@@H](CCC(O)=O)C(N)=O)=O)CCC7
Pathway
– Others
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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