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Xylometazoline (hydrochloride)
SKU
HY-B0475-1 g
Category Reference compound
Tags Adrenergic Receptor, GPCR/G Protein;Neuronal Signaling, Inflammation/Immunology
$55 – $96
Products Details
Product Description
– Xylometazoline hydrochloride is an α-adrenergic receptor agonist (Ki=0.05-1.7 μM). Xylometazoline hydrochloride can constrict nasal blood vessels and increase nasal airflow. Xylometazoline hydrochloride can be used in nose stuffiness and runny nose research[1][2].
Web ID
– HY-B0475
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C16H25ClN2
References
– [1]Ronald Eccles, et al. The nasal decongestant effect of xylometazoline in the common cold. Am J Rhinol. 2008 Sep-Oct;22(5):491-6.|[2]Britta Haenisch, et al. Alpha-adrenoceptor agonistic activity of oxymetazoline and xylometazoline. Fundam Clin Pharmacol. 2010 Dec;24(6):729-39.
CAS Number
– 1218-35-5
Molecular Weight
– 280.84
Compound Purity
– 99.58
SMILES
– CC1=C(CC2=NCCN2)C(C)=CC(C(C)(C)C)=C1.Cl
Clinical Information
– Launched
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 25 mg/mL (ultrasonic)|H2O : 50 mg/mL (ultrasonic)
Target
– Adrenergic Receptor
Isoform
– α adrenergic receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.