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Products Details
Product Description
– Xanthoplanine, isolated from theroot of Xylopia parviflora, fully inhibits the EC50 ACh responses of both alpha7 and alpha4beta2 nACh receptors with estimated IC50 values of 9 μM (alpha7) and 5 μM (alpha4beta2)[1].
Web ID
– HY-N1064
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C21H26NO4
References
– [1]Iturriaga-Vásquez P, et al. Aporphine metho salts as neuronal nicotinic acetylcholine receptor blockers.Bioorg Med Chem. 2007 May 15;15(10):3368-72.
CAS Number
– 6872-88-4
Molecular Weight
– 356.43
SMILES
– C[N+]1(C)CCC2=CC(OC)=C(OC)C3=C2[C@]1([H])CC4=CC(O)=C(OC)C=C34
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– nAChR
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
