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Xanthohumol I
SKU
HY-N10917-Get quote
Category Natural Products
Tags Cancer; Infection, Cholinesterase (ChE), Neuronal Signaling
Products Details
Product Description
– Xanthohumol I, a chalkone, is a derivative of Xanthohumol (HY-N1067). Xanthohumol is a Cholinesterase (ChE) inhibitor, which inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) wih IC50s of 71.34 μM and 32.67 μM, respectively. The hydroxy compound of Xanthohumol (3-hydroxy-xanthohumol), also shoes inhibitory effect on AChE and BChE with IC50s of 51.25 μM and 63.07 μM[1].
Web ID
– HY-N10917
Shipping
– Room temperature
Molecular Formula
– C21H22O6
References
– [1]Orhan IE, et al. Molecular modeling and in vitro approaches towards cholinesterase inhibitory effect of some natural xanthohumol, naringenin, and acyl phloroglucinol derivatives. Phytomedicine. 2018 Mar 15;42:25-33.
CAS Number
– 688360-06-7
Molecular Weight
– 370.40
SMILES
– OC1=CC=C(/C=C/C(C2=C3OC(C(C)(O)C)CC3=C(O)C=C2OC)=O)C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection
Solubility
– 10 mM in DMSO
Target
– Cholinesterase (ChE)
Isoform
– AChE;BChE
Pathway
– Neuronal Signaling
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.