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WYE-354
Price range: 69 CAD through 613 CAD
Products Details
Product Description
– WYE-354(IC50=5 nM) is an effective, selective and ATP-competitive mTOR inhibitor. It blocks mTORC2/P-AKT(S473) and mTORC1/P-S6K(T389), not P-AKT(T308). The selectivity for mTOR is higher than PI3Kα (>100-fold) and PI3Kγ (>500-fold).
Web ID
– T6731
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H29N7O5
Citations
– 1. Chen W, Liao Y, Sun P, et al.Construction of an ER stress-related prognostic signature for predicting prognosis and screening the effective anti-tumor drug in osteosarcoma.Journal of Translational Medicine.2024, 22(1): 1-19.
References
– Yu K, et al. Cancer Res, 2009, 69(15), 6232-6240.
CAS Number
– 1062169-56-5
Molecular Weight
– C24H29N7O5
Compound Purity
– 0.9831
SMILES
– COC(=O)Nc1ccc(cc1)-c1nc(N2CCOCC2)c2cnn(C3CCN(CC3)C(=O)OC)c2n1
Pathway
– Apoptosis|||Autophagy|||PI3K/Akt/mTOR signaling
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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