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Wychimicin C
Products Details
Product Description
– Wychimicin C is a spirotetronate polyketide, can be isolated from the rare actinomycete Actinocrispum wychmicini strain MI503-AF4. Wychimicin C shows strong antibacterial activity against methicillin-resistant Staphylococcus. aureus (IC50=0.125-0.5 μg/mL) and Enterococcus. faecalis/faecium (IC50=0.125-0.25 μg/mL)[1][2].
Web ID
– HY-N10560
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C46H58ClNO11
References
– [1]Kimura T, et al. Wychimicins, a new class of spirotetronate polyketides from Actinocrispum wychmicini MI503-A4. J Antibiot (Tokyo). 2022 Oct;75(10):535-541. |[2]Hatano M, et al. Actinocrispum wychmicini gen. nov., sp. nov., a novel member of the family Pseudonocardiaceae, isolated from soil. Int J Syst Evol Microbiol. 2016 Nov;66(11):4779-4784.
Molecular Weight
– 836.41
SMILES
– OC1=C(C(C)=C(C=C1)Cl)C(N[C@@H]2[C@H](O[C@H](C[C@@H]2O)O[C@]([H])(C/C=C/C3[C@@]4([C@]5([C@]([H])(C=C3CC)[C@H]([C@H](C[C@@H]5C)O)O)[H])C)/C(C)=C/[C@H]6[C@]7(C[C@@H](C=C6)C)C(O)=C(C(O7)=O)C4=O)C)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Natural Products
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