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Verminoside
$310
Only 1000 item(s) left in stock.
Products Details
Product Description
– Verminoside is an iridoid isolated from Kigelia africana, exhibits anti-inflammatory and remarkable antioxidant activity with a radical-scavenging activity of 2.5 μg/mL. The genotoxicity of Verminoside on human lymphocytes is associated with elevated levels of PARP-1 and p53 proteins[1][2][3].
Web ID
– HY-N1094
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C24H28O13
References
– [1]Boniface PK, et al. RP-HPLC-DAD method for the identification of two potential antioxidant agents namely verminoside and 1-O-(E)-caffeoyl-β-gentiobiose from Spathodea campanulata leaves. Nat Prod Res. 2015;29(7):676-80.|[2]Santoro A, et al. Verminoside- and verbascoside-induced genotoxicity on human lymphocytes: involvement of PARP-1 and p53 proteins. Toxicol Lett. 2008 May 5;178(2):71-6.|[3]Picerno P, et al. Anti-inflammatory activity of verminoside from Kigelia africana and evaluation of cutaneous irritation in cell cultures and reconstituted human epidermis. J Nat Prod. 2005 Nov;68(11):1610-4.
CAS Number
– 50932-19-9
Molecular Weight
– 524.47
Compound Purity
– 98.0
SMILES
– OC[C@@]12[C@H]([C@@H](OC(/C=C/C3=CC(O)=C(O)C=C3)=O)[C@@]4([H])[C@]2([H])[C@@H](OC=C4)O[C@]5([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]5O)CO)O1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– MDM-2/p53;PARP
Isoform
– PARP1
Pathway
– Apoptosis;Cell Cycle/DNA Damage;Epigenetics
Product type
– Natural Products
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
