Vancomycin (hydrochloride)

$60$190

Products Details

Product Description

– Vancomycin hydrochloride is an antibiotic for the treatment of bacterial infections. It acts by inhibiting the second stage of cell wall synthesis of susceptible bacteria. Vancomycin also alters the permeability of the cell membrane and selectively inhibits ribonucleic acid synthesis.

Web ID

– HY-17362

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C66H76Cl3N9O24

Citations

– Front Aging Neurosci. 2022 Jul 28;14:858130.|Pol J Microbiol. 2023 Jun 14;72(2):199-208.|Redox Biol. 2023 Oct 10, 102929.|Small. 2021 Dec 19;e2107137.|ACS Infect Dis. 2021 Aug 4.|ACS Infect Dis. 2023 Nov 28.|ACS Omega. 2023 Feb 2; 8 (6), 5415-5425.|ACS Omega. 2023 Mar 6.|ACS Omega. March 3, 2022.|Appl Microbiol Biotechnol. 2022 Apr;106(7):2689-2702.|Aquaculture. 2021, 736248.|Cell Death Dis. 2021 Jun 7;12(6):582.|Cell Metab. 2023 Sep 29:S1550-4131(23)00340-6.|Chemosphere. 2019 Jun;225:378-387. |Curr Microbiol. 2023 May 31;80(7):230.|Emerg Microbes Infect. 2022 Feb 22;1-34.|Environ Health Perspect. 2022 Jun;130(6):67009.|Front Microbiol. 2020 Jul 31;11:1720.|Genome Biol. 2023 Apr 30;24(1):98.|Gut Microbes. 2023 Dec;15(2):2249143.|Infect Drug Resist. 2021 Dec 16;14:5449-5456.|Int J Med Microbiol. 2020 Jan;69(1):120-131.|Int J Med Sci. 2022 Apr 11;19(4):740-752.|iScience. 2023 Mar.|iScience. 2023 Oct 5.|iScience. 5 January 2022, 103731.|J Cell Physiol. 2021 Dec 8.|J Pharm Anal. 2023 Jun 16.|Life Sci. 2020 Nov 15;261:118473.|Microb Biotechnol. 2021 Mar 15.|Microbiol Spectr. 2022 Mar 2;e0054121.|Mol Immunol. 2022 Jul 6;149:94-106.|Mol Pharm. 2022 Oct 21.|Research Square Preprint. 2020 Jun.|Transl Res. 2022 Sep 5;S1931-5244(22)00198-0.

References

– [1]Rybak MJ, et al. The pharmacokinetic and pharmacodynamic properties of vancomycin. Clin Infect Dis. 2006 Jan 1;42 Suppl 1:S35-9.|[2]Watanakunakorn C, et al. Mode of action and in-vitro activity of vancomycin. J Antimicrob Chemother. 1984 Dec;14 Suppl D:7-18.|[3]Warren CA, et al. Vancomycin treatment’s association with delayed intestinal tissue injury, clostridial overgrowth, and recurrence of Clostridium difficile infection in mice. Antimicrob Agents Chemother. 2013 Feb;57(2):689-96.

CAS Number

– 1404-93-9

Molecular Weight

– 1485.71

Compound Purity

– 99.43

SMILES

– ClC1=CC([C@H]([C@@H](NC([C@H](NC)CC(C)C)=O)C(N[C@@H](CC(N)=O)C(N[C@@]2([H])C(N[C@]3([H])C4=CC(C5=C(C=C(O)C=C5O)[C@](C(O)=O)([H])NC([C@](NC3=O)([H])[C@H](O)C6=CC=C7C(Cl)=C6)=O)=C(O)C=C4)=O)=O)=O)O)=CC=C1OC8=C(C(O7)=CC2=C8)O[C@H]9[C@@H]([C@H]([C@H](O)[C@@H](CO)O9)O)O[C@@]%10([H])C[C@](N)([C@H](O)[C@H](C)O%10)C.Cl

Clinical Information

– Launched

Research Area

– Infection; Cancer

Solubility

– DMSO : 24 mg/mL (ultrasonic;warming)|H2O : 33.33 mg/mL (ultrasonic)

Target

– Antibiotic;Autophagy;Bacterial

Isoform

– Glycopeptide

Pathway

– Anti-infection;Autophagy

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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