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Valproic Acid
80 CAD
Products Details
Product Description
– Valproic Acid (2-Propylpentanoic Acid) is an HDAC inhibitor that inhibits HDAC1 activity, induces HDAC2 degradation, and is orally active. Valproic Acid can be used in epilepsy and bipolar disorder research.
Web ID
– T7064
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C8H16O2
Citations
– 1. Zhu Z A, Li Y Y, Xu J, et al.CDKL5 deficiency in adult glutamatergic neurons alters synaptic activity and causes spontaneous seizures via TrkB signaling.Cell Reports.2023, 42(10).
2. Han L, Song B, Zhang P, et al.PC3T: a signature-driven predictor of chemical compounds for cellular transition.Communications Biology.2023, 6(1): 989.
3. Li G, Zeng M, Yan Z, et al.HDAC inhibitors support long-term expansion of porcine hepatocytes in vitro.Biomedicine & Pharmacotherapy.2024, 177: 116973.
References
– Shoji M, et al. Valproic acid, a histone deacetylase inhibitor, enhances radiosensitivity in esophageal squamous cell carcinoma. Int J Oncol. 2012 Jun;40(6):2140-6.
CAS Number
– 99-66-1
Molecular Weight
– C8H16O2
Compound Purity
– 0.9949
SMILES
– CCCC(CCC)C(O)=O
Pathway
– DNA Damage/DNA Repair|||Chromatin/Epigenetic|||Autophagy|||Membrane transporter/Ion channel|||Microbiology/Virology|||Neuroscience|||Proteases/Proteasome|||Stem Cells
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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