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Valinomycin
Price range: 53 CAD through 318 CAD
Products Details
Product Description
– Valinomycin (NSC-122023) is a cyclic depsipeptide antibiotic and a potassium-specific ionophore.Valinomycin induces PINK1 activation and promotes Parkin phosphorylation at Ser65.
Web ID
– TP1072
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C54H90N6O18
Citations
– 1. Chen X C, Tang G X, Luo W H, et al. Monitoring and Modulating mtDNA G-Quadruplex Dynamics Reveal Its Close Relationship to Cell Glycolysis. Journal of the American Chemical Society. 2021
2. Li X, Li X, Xiang C, et al.Starvation-induced phosphorylation activates gasdermin A to initiate pyroptosis.Cell Reports.2024, 43(9).
References
– Kondapalli C, et al. PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65. Open Biol. 2012 May;2(5):120080.
CAS Number
– 2001-95-8
Molecular Weight
– C54H90N6O18
Compound Purity
– 0.9716
SMILES
– CC(C)[C@@H]1NC(=O)[C@@H](C)OC(=O)[C@H](NC(=O)[C@@H](OC(=O)[C@@H](NC(=O)[C@@H](C)OC(=O)[C@H](NC(=O)[C@@H](OC(=O)[C@@H](NC(=O)[C@@H](C)OC(=O)[C@H](NC(=O)[C@@H](OC1=O)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C
Pathway
– Microbiology/Virology|||Apoptosis|||Autophagy|||PI3K/Akt/mTOR signaling
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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