Vactosertib
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Vactosertib

SKU T6496-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 62 CAD through 1,968 CAD

Products Details

Product Description

– Vactosertib (EW-7197) is an orally bioavailable inhibitor of the serine/threonine kinase, transforming growth factor (TGF)-beta receptor type 1 (TGFBR1), also known as activin receptor-like kinase 5 (ALK5), with potential antineoplastic activity.

Web ID

– T6496

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H18FN7

Citations

– 1. Kalli M, Mpekris F, Wong C K, et al. Activin A signaling regulates IL13Rα2 expression to promote breast cancer metastasis. Frontiers in Oncology. 2019 Feb 5;9:32

References

– Jin CH, et al. J Med Chem. 2014, 57(10), 4213-4238.

CAS Number

– 1352608-82-2

Molecular Weight

– C22H18FN7

Compound Purity

– 0.9955

SMILES

– Cc1cccc(n1)-c1[nH]c(CNc2ccccc2F)nc1-c1ccc2ncnn2c1

Pathway

– Stem Cells|||Angiogenesis|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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