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Products Details
Product Description
– Uncarinic acid E has anti-cancer activity, it induces apoptosis in HepG2 cells via accumulation of p53, alters the Bax/Bcl-2 ratio, and activates caspases, resulting in cytochrome c release from the mitochondria. A mixture of uncarinic acid E and 27-O-p-(E)-coumaroyloxyursolic acid exhibits antiplasmodial activity, with the IC50 value of 2.9 microg/ml.
Web ID
– TN5201
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C39H54O6
CAS Number
– 277751-61-8
Molecular Weight
– C39H54O6
SMILES
– CC1(C)CC[C@@]2(CC[C@]3(COC(=O)C=Cc4ccc(O)cc4)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1)C(O)=O
Pathway
– Proteases/Proteasome|||Apoptosis|||MAPK|||Microbiology/Virology|||PI3K/Akt/mTOR signaling
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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