UNC1999
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UNC1999

SKU T3057-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 50 CAD through 1,904 CAD

Products Details

Product Description

– UNC1999 is a orally bioavailable, effective and specific inhibitor of EZH2 (IC50=2 nM) and EZH1 (IC50=45).

Web ID

– T3057

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C33H43N7O2

Citations

– 1. Yan Y, Tian M, Li M, et al. ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder. Neuron. 2022 2. Chen J, Xu L, Li W, et al.AKR1B1 is Required for Maintaining Acute Leukemia Cell Survival by Epigenetic Silencing of Tumor Suppressor Genes.Biochemical Genetics.2024: 1-21.

References

– Konze KD, et al. ACS Chem. Biol. 2013, 8 (6), 1324–1334.

CAS Number

– 1431612-23-5

Molecular Weight

– C33H43N7O2

Compound Purity

– 0.997

SMILES

– CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C(C)C)-c1ccc(nc1)N1CCN(CC1)C(C)C

Pathway

– Chromatin/Epigenetic|||Autophagy

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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