Download Files:
UNC1215
SKU
HY-15649-10 mg
Category Reference compound
Tags Apoptosis;Epigenetics, Apoptosis;Histone Methyltransferase, Cancer
$96 – $617
Products Details
Product Description
– UNC1215 is a potent and selective inhibitor for the methyllysine (Kme) reading domain function of L3MBTL3 with a Kd value of 120 nM and an IC50 of 40 nM. UNC1215 has the potential to treat malignant brain tumor.
Web ID
– HY-15649
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C32H43N5O2
References
– [1]James LI, Barsyte-Lovejoy D, Zhong N, et al. Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain. Nat Chem Biol. 2013 Mar;9(3):184-91. doi: 10.1038/nchembio.1157.
CAS Number
– 1415800-43-9
Molecular Weight
– 529.72
Compound Purity
– 98.47
SMILES
– O=C(C1=CC=C(C(N2CCC(N3CCCC3)CC2)=O)C=C1NC4=CC=CC=C4)N5CCC(N6CCCC6)CC5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 270 mg/mL
Target
– Apoptosis;Histone Methyltransferase
Pathway
– Apoptosis;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.