UCM 608

$100$830

Products Details

Product Description

– UCM 608 is a high affinity melatonin (MT) membrane receptor agonist. The pKi values for MT1 and MT2 are 10.7 and 10.4[1][2].

Web ID

– HY-101074

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C19H20N2O2

References

– [1]Mor, M., et al. Synthesis, pharmacological characterization and QSAR studies on 2-substituted indole melatonin receptor ligands. Bioorganic & Medicinal Chemistry, 9(4), 1045–1057.|[2] Radogna F, et al. Rapid and transient stimulation of intracellular reactive oxygen species by melatonin in normal and tumor leukocytes. Toxicol Appl Pharmacol. 2009;239(1):37-45.

CAS Number

– 151889-03-1

Molecular Weight

– 308.37

Compound Purity

– 99.18

SMILES

– CC(NCCC1=C(C2=CC=CC=C2)NC3=C1C=C(OC)C=C3)=O

Clinical Information

– No Development Reported

Research Area

– Cancer; Inflammation/Immunology; Neurological Disease

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– Melatonin Receptor

Isoform

– MT1;MT2

Pathway

– GPCR/G Protein;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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