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UCM 608
SKU
HY-101074-10 mg
Category Reference compound
Tags Cancer; Inflammation/Immunology; Neurological Disease, GPCR/G Protein;Neuronal Signaling, Melatonin Receptor
$100 – $830
Products Details
Product Description
– UCM 608 is a high affinity melatonin (MT) membrane receptor agonist. The pKi values for MT1 and MT2 are 10.7 and 10.4[1][2].
Web ID
– HY-101074
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C19H20N2O2
References
– [1]Mor, M., et al. Synthesis, pharmacological characterization and QSAR studies on 2-substituted indole melatonin receptor ligands. Bioorganic & Medicinal Chemistry, 9(4), 1045–1057.|[2] Radogna F, et al. Rapid and transient stimulation of intracellular reactive oxygen species by melatonin in normal and tumor leukocytes. Toxicol Appl Pharmacol. 2009;239(1):37-45.
CAS Number
– 151889-03-1
Molecular Weight
– 308.37
Compound Purity
– 99.18
SMILES
– CC(NCCC1=C(C2=CC=CC=C2)NC3=C1C=C(OC)C=C3)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology; Neurological Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Melatonin Receptor
Isoform
– MT1;MT2
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.