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UC-112
$140 – $1,350
Products Details
Product Description
– UC-112 is a new and highly effective inhibitor of apoptosis inhibitory protein IAP, with an IC50 value of 0.7-3.4uM in cancer cells.
Web ID
– HY-12842
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C22H24N2O2
References
– [1]Wang J, et al. Discovery of novel second mitochondria-derived activator of caspase mimetics as selective inhibitor of apoptosis protein inhibitors. J Pharmacol Exp Ther. 2014 May;349(2):319-29.|[2]Qinghui Wang, et al. Synthesis and biological evaluation of indole-based UC-112 analogs as potent and selective survivin inhibitors. Eur J Med Chem
CAS Number
– 383392-66-3
Molecular Weight
– 348.44
Compound Purity
– 99.72
SMILES
– OC1=C2N=CC=CC2=C(COCC3=CC=CC=C3)C=C1CN4CCCC4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 33.33 mg/mL (ultrasonic)
Target
– Apoptosis;IAP
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
