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U18666A
Price range: 46 CAD through 1,042 CAD
Products Details
Product Description
– U18666A is a cell-permeable drug and is a cholesterol synthesis and transport inhibitor. It inhibits replication of Ebola virus, dengue virus, and human hepatitis C virus.
Web ID
– T17190
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C25H42ClNO2
Citations
– 1. Zhao X, Lian X, Xie J, et al.Accumulated cholesterol protects tumours from elevated lipid peroxidation in the microenvironment.Redox Biology.2023: 102678.
2. Guo Y, Chen Y, Wang Q, et al.Emodin and rhapontigenin inhibit the replication of African swine fever virus by interfering with virus entry.Veterinary Microbiology.2023: 109794.
3. Liu Q, Chen S, Tian R, et al.3β-hydroxysteroid-Δ24 reductase dampens anti-viral innate immune responses by targeting K27 ubiquitination of MAVS and STING.Journal of Virology.2023: e01513-23.
References
– Poh MK, et al. U18666A, an intra-cellular cholesterol transport inhibitor, inhibits dengue virus entry and replication. Antiviral Res. 2012 Jan;93(1):191-8.
CAS Number
– 3039-71-2
Molecular Weight
– C25H42ClNO2
Compound Purity
– 0.9899
SMILES
– Cl.[H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@H](CC[C@]12C)OCCN(CC)CC
Target
– PI3K
Pathway
– Proteases/Proteasome|||Microbiology/Virology
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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