Tuxobertinib
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Tuxobertinib

SKU T9072-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 54 CAD through 1,267 CAD

Products Details

Product Description

– Tuxobertinib (BDTX-189) is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations, with KDs of 0.2, 0.76, 13, and 1.2 nM for EGFR, HER2, BLK, and RIPK2, respectively, and exhibits anticancer activity.

Web ID

– T9072

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C29H29ClN6O4

References

– Elizabeth Buck, et al. BDTX-189, a Potent and Selective Inhibitor of Allosteric EGFR and HER2 Oncogenic Mutations.

CAS Number

– 2414572-47-5

Molecular Weight

– C29H29ClN6O4

Compound Purity

– 0.9922

SMILES

– Clc1cc(Nc2ncnc3cc(OCCN4CCOCC4)c(NC(=O)C=C)cc23)ccc1OCc1ccccn1

Pathway

– Apoptosis|||JAK/STAT signaling|||Angiogenesis|||NF-κB|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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