TUG-499

SKU T60184-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 48 CAD through 666 CAD

Products Details

Product Description

– TUG-499 is a selective free fatty acid receptor 1 (FFAR1 or GPR40) agonist (EC50: 7.39). It shows higher affinity for FFAR1 or GPR40 relative to related receptors FFA2, FFA3, and the nuclear receptor PPARγ, as well as various other receptors, ion channels, and transporter proteins. TUG-499 is useful for studying Type 2 diabetes.

Web ID

– T60184

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C16H11Cl2NO2

References

– Christiansen E, et al. Identification of a potent and selective free fatty acid receptor 1 (FFA1/GPR40) agonist with favorable physicochemical and in vitro ADME properties. J Med Chem. 2011;54(19):6691-6703.

CAS Number

– 1206629-08-4

Molecular Weight

– C16H11Cl2NO2

Compound Purity

– 0.9959

SMILES

– C(#CC1=CC=C(CCC(O)=O)C=C1)C=2C=C(Cl)N=C(Cl)C2

Pathway

– Endocrinology/Hormones|||GPCR/G Protein|||Metabolism|||DNA Damage/DNA Repair

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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