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TTNPB
$66 – $396
Products Details
Product Description
– TTNPB is a highly potent RAR agonist. Competitive binding assays using human RARs yield IC50s of α=5.1 nM, β= 4.5 nM, and γ=9.3 nM, respectively.
Web ID
– HY-15682
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C24H28O2
References
– [1]Pignatello MA, et al. Multiple factors contribute to the toxicity of the aromatic retinoid, TTNPB (Ro 13-7410): binding affinities and disposition. Toxicol Appl Pharmacol. 1997 Feb;142(2):319-27.
CAS Number
– 71441-28-6
Molecular Weight
– 348.48
Compound Purity
– 98.97
SMILES
– O=C(O)C1=CC=C(/C=C(C2=CC=C3C(C)(C)CCC(C)(C)C3=C2)C)C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 8.33 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Apoptosis;Autophagy;RAR/RXR
Pathway
– Apoptosis;Autophagy;Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
