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Products Details
Product Description
– TSPO ligand-2 is a ligand of AUTAC1. AUTAC1 contains an p-fluorobenzylguanine (FBnG) and a Fumagillol moiety, which can silence endogenous MetAP2 in HeLa cells[1].
Web ID
– HY-150409
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C23H29NO8
References
– [1]Takahashi D, et al. AUTACs: Cargo-Specific Degraders Using Selective Autophagy. Mol Cell. 2019 Dec 5;76(5):797-810.e10.
CAS Number
– 1160640-95-8
Molecular Weight
– 447.48
Compound Purity
– 99.63
SMILES
– O=C(O[C@H]1[C@@H](OC)[C@@]([C@]2(C)[C@@H](C/C=C(C)C)O2)([H])[C@]3(OC3)CC1)OC4=CC=C([N+]([O-])=O)C=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 50 mg/mL (ultrasonic;warming;heat to 70°C)
Target
– AUTACs
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.