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TRV-120027 acetate (1234510-46-3 free base)
Price range: 160 CAD through 4,112 CAD
Products Details
Product Description
– TRV-120027 acetate is a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1 receptor) and engages -arrestins while blocking G-protein signaling.
Web ID
– TP2158L1
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C45H71N13O12
References
– Boerrigter G, et al. TRV120027, a novel β-arrestin biased ligand at the angiotensin II type I receptor, unloads the heart and maintains renal function when added to furosemide in experimental heart failure.Circ Heart Fail. 2012 Sep 1;5(5):627-34. Epub 2012 Aug 13.
CAS Number
– 1824712-70-0
Molecular Weight
– C45H71N13O12
Compound Purity
– 0.9934
SMILES
– CC(O)=O.C[C@H](C(O)=O)NC([C@H]1N(C([C@H](CC2=CNC=N2)NC([C@H]([C@@H](C)CC)NC([C@H](CC3=CC=C(O)C=C3)NC([C@H](C(C)C)NC([C@H](CCCNC(N)=N)NC(CNC)=O)=O)=O)=O)=O)=O)CCC1)=O
Pathway
– Endocrinology/Hormones|||GPCR/G Protein
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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