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Tripelennamine (hydrochloride)

$84$624

Products Details

Product Description

– Tripelennamine hydrochloride, an ethylenediamine derivative, is a potent histamine H1-receptor antagonist. Tripelennamine hydrochloride lessens the allergic response of the organism caused by histamine. Tripelennamine hydrochloride can be used for the research of rhinitis, conjunctivitis, and allergic and anaphylactic reactions[1][2][3].

Web ID

– HY-17428

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C16H22ClN3

References

– [1]Manohar M, et al. H1-receptor antagonist, tripelennamine, does not affect arterial hypoxemia in exercising Thoroughbreds. J Appl Physiol. 2002 Apr;92(4):1515-23.|[2]Wasfi IA, et al. Comparative disposition of tripelennamine in horses and camels after intravenous administration. J Vet Pharmacol Ther. 2000 Jun;23(3):145-52.|[3]Yeh SY, et al. The pharmacokinetics of pentazocine and tripelennamine. Clin Pharmacol Ther. 1986 Jun;39(6):669-76.

CAS Number

– 154-69-8

Molecular Weight

– 291.82

Compound Purity

– 99.90

SMILES

– CN(C)CCN(CC1=CC=CC=C1)C2=NC=CC=C2.[H]Cl

Clinical Information

– Launched

Research Area

– Inflammation/Immunology; Endocrinology

Solubility

– DMSO : 25 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)

Target

– Endogenous Metabolite;Histamine Receptor

Isoform

– H1 Receptor

Pathway

– GPCR/G Protein;Immunology/Inflammation;Metabolic Enzyme/Protease;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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