Trimethylamine N-oxide

SKU T41245-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 46 CAD through 48 CAD

Products Details

Product Description

– Trimethylamine N-oxide (TMAO) is a colorless amine oxide produced from choline, betaine, and carnitine via intestinal microbial metabolism that accumulates in tissues of marine animals and prevents the protein-damaging effects of urea.Trimethylamine N-oxide induces inflammation through activation of ROS/NLRP3 inflammasomes, which can induce fibroblast differentiation and cardiac fibrosis.

Web ID

– T41245

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C3H9NO

References

– Wei Shuai, et al. High-choline Diet Exacerbates Cardiac Dysfunction, Fibrosis, and Inflammation in a Mouse Model of Heart Failure With Preserved Ejection Fraction. J Card Fail. 2020 May 14;S1071-9164(19)31802-0.

CAS Number

– 1184-78-7

Molecular Weight

– C3H9NO

SMILES

– C[N+](C)(C)[O-]

Pathway

– Immunology/Inflammation|||NF-κB|||Metabolism|||Stem Cells

Product type

– Natural Product

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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