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Products Details
Product Description
– Triclabendazole sulfoxide (TCBZ-SO) is the main plasma metabolite of Triclabendazole, and exhibits anti-parasite effects. Triclabendazole sulfoxide can inhibit membrane transporter ABCG2/BCRP[1][2].
Web ID
– HY-136450
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C14H9Cl3N2O2S
References
– [1]Barrera B, et, al. The anthelmintic triclabendazole and its metabolites inhibit the membrane transporter ABCG2/BCRP. Antimicrob Agents Chemother. 2012 Jul;56(7):3535-43.|[2]Robinson MW, et, al. The comparative metabolism of triclabendazole sulphoxide by triclabendazole-susceptible and triclabendazole-resistant Fasciola hepatica. Parasitol Res. 2004 Feb;92(3):205-10.
CAS Number
– 100648-13-3
Molecular Weight
– 375.66
SMILES
– O=S(C1=NC2=CC(OC3=CC=CC(Cl)=C3Cl)=C(Cl)C=C2N1)C
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– BCRP;Parasite
Pathway
– Anti-infection;Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
