Trichodesmine

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Products Details

Product Description

– Trichodesmine is a dehydropyrrolizidine alkaloid. Trichodesmine can produces hepatotoxicty, pneumo- and neurotoxicity in vivo[1][2].

Web ID

– HY-12535

Shipping

– Room temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C18H27NO6

References

– [1]Cooper RA, et, al. The relationship between reactivity of metabolites of pyrrolizidine alkaloids and extrahepatic toxicity. Proc West Pharmacol Soc. 1999;42:13-6.|[2]Pessoa CRM, et, al. Pulmonary and hepatic lesions caused by the dehydropyrrolizidine alkaloid-producing plants Crotalaria juncea and Crotalaria retusa in donkeys. Toxicon. 2013 Sep;71:113-20.

CAS Number

– 548-90-3

Molecular Weight

– 353.41

SMILES

– O=C(O[C@]1([H])CCN2[C@]1([H])C(CO3)=CC2)[C@H](C(C)C)[C@@](C)(O)[C@@](C)(O)C3=O

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease; Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Others

Pathway

– Others

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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